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ACVRL1 antibody

CAT: 0710-FNab00131Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00131Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
Synonyms
Serine/threonine-protein kinase receptor R3 (SKR3) |Activin receptor-like kinase 1 (ALK-1) |TGF-B superfamily receptor type I (TSR-I) |ACVRL1|ACVRLK1|ALK1
Gene ID
94
UniProt
P37023
Host
Rabbit
Reactivity
Human
Immunogen
Activin A receptor type II-like 1
Target
ACVRL1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, FC, IP
Field of Research
Cardiovascular, Metabolism, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:1000; IHC: 1:100-1:400; IP: 1:200-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
56 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, FC, IP

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