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ACP3 antibody

CAT: 0710-FNab00102Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00102Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.
Synonyms
Prostatic acid phosphatase (PAP) |5'-nucleotidase (5'-NT) |Acid phosphatase 3|Ecto-5'-nucleotidase|Protein tyrosine phosphatase ACP3|Thiamine monophosphatase (TMPase) |PAPf39|ACP3|ACPP
Gene ID
55
UniProt
P15309
Host
Mouse
Reactivity
Human, rat
Immunogen
Acid phosphatase, prostate
Target
ACP3
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, WB, IHC
Field of Research
Cancer, Immunology, Metabolism
Purification
Protein A+G purification
Dilution
WB: 1:200-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
48 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
8D6
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
27-373aa

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