ACO2 antibody

CAT: 0710-FNab00088Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab00088Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ACO2 (aconitate hydratase, mitochondrial) is also named as citrate hydro-lyase and belongs to the aconitase/IPM isomerase family. It plays a key function in cellular energy production, and loss of its activity has a major impact on cellular and organismal survival. Western blot shows two bands of 83 kDa and 40 kDa. The 40 kDa fragment decreases with age and oxidative stress, whereas other fragmentation products with molecular weights between 40 and 83 kDa increased with age and MnSOD (mitochondrial manganese superoxide dismutase) deficiency (PMID:12459471) . Defects in ACO2 are the cause of infantile cerebellar-retinal degeneration (ICRD) .
Synonyms
Aconitate hydratase, mitochondrial (Aconitase) |Citrate hydro-lyase|ACO2
Gene ID
50
UniProt
Q99798
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Aconitase 2, mitochondrial
Target
ACO2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
85 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
51-246aa

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