ACACA antibody

• Background:

  ACACA (Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase (FAS) (PMID:19900410) . It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.

• Synonyms:

  Acetyl-CoA carboxylase 1 (ACC1) |Acetyl-Coenzyme A carboxylase alpha (ACC-alpha) |ACACA|ACAC|ACC1|ACCA

• Gene ID:

  31

• UniProt:

  Q13085

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Acetyl-Coenzyme A carboxylase alpha

• Target:

  ACACA

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF

• Field of Research:

  Cardiovascular, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  270 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF

• Immunogen Sequence:

  2223-2346aa