Doxercalciferol-d3

Doxercalciferol-d3

• UNSPSC Description: Doxercalciferol-d33 is the deuterated form of Doxercalciferol, which is a Vitamin D2 analog that acts as a vitamin D receptor activator (VDRA).
• Target Antigen: VD/VDR
• Type: Isotope-Labeled Compounds
• Related Pathways: Vitamin D Related/Nuclear Receptor
• Field of Research: Metabolic Disease
• Solubility: 10 mM in DMSO
• Smiles: O[C@@H](C[C@H](O)C1)C(/C1=C([2H])\C=C2[C@@]3([H])[C@@](CCC\2)(C)[C@@H]([C@H](C)/C=C/[C@H](C)C(C)C)CC3)=C([2H])\[2H]
• Molecular Weight: 415.67
• References & Citations: [1]Brown AJ, Ritter CS, Knutson JC, Strugnell SA.
 The vitamin D prodrugs 1alpha(OH)D2, 1alpha(OH)D3 and BCI-210 suppress PTH secretion by bovine parathyroid cells.
 Nephrol Dial Transplant. 2006 Mar;21(3):644-50.|[2]Noonan W, Koch K, Nakane M, Ma J, Dixon D, Bolin A, Reinhart G.
 Differential effects of vitamin D receptor activators on aortic calcification and pulse wave velocity in uraemic rats.
 Nephrol Dial Transplant. 2008 Dec;23(12):3824-30.|[3]Sj?dén G.
 Effects of vitamin D. A comparison of 1 alpha OHD2 and 1 alpha OHD3 in rats.
 Acta Orthop Scand Suppl. 1985;217:1-84.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported