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Doxercalciferol-d3

CAT: 0804-HY-15285-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15285-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Doxercalciferol-d33 is the deuterated form of Doxercalciferol, which is a Vitamin D2 analog that acts as a vitamin D receptor activator (VDRA) .
UNSPSC
12352211
Target
VD/VDR
Type
Isotope-Labeled Compounds
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Solubility
10 mM in DMSO
Smiles
O[C@@H](C[C@H](O)C1)C(/C1=C([2H])\C=C2[C@@]3([H])[C@@](CCC\2)(C)[C@@H]([C@H](C)/C=C/[C@H](C)C(C)C)CC3)=C([2H])\[2H]
Molecular Formula
C28H41D3O2
Molecular Weight
415.67
References & Citations
[1]Brown AJ, Ritter CS, Knutson JC, Strugnell SA. The vitamin D prodrugs 1alpha (OH) D2, 1alpha (OH) D3 and BCI-210 suppress PTH secretion by bovine parathyroid cells. Nephrol Dial Transplant. 2006 Mar;21 (3) :644-50.|[2]Noonan W, Koch K, Nakane M, Ma J, Dixon D, Bolin A, Reinhart G. Differential effects of vitamin D receptor activators on aortic calcification and pulse wave velocity in uraemic rats. Nephrol Dial Transplant. 2008 Dec;23 (12) :3824-30.|[3]Sj?dén G. Effects of vitamin D. A comparison of 1 alpha OHD2 and 1 alpha OHD3 in rats. Acta Orthop Scand Suppl. 1985;217:1-84.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported