Doxercalciferol-d3

• UNSPSC Description:

  Doxercalciferol-d33 is the deuterated form of Doxercalciferol, which is a Vitamin D2 analog that acts as a vitamin D receptor activator (VDRA).

• Target Antigen:

  VD/VDR

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Field of Research:

  Metabolic Disease

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@@H](C[C@H](O)C1)C(/C1=C([2H])\C=C2[C@@]3([H])[C@@](CCC\2)(C)[C@@H]([C@H](C)/C=C/[C@H](C)C(C)C)CC3)=C([2H])\[2H]

• Molecular Weight:

  415.67

• References & Citations:

  [1]Brown AJ, Ritter CS, Knutson JC, Strugnell SA. The vitamin D prodrugs 1alpha(OH)D2, 1alpha(OH)D3 and BCI-210 suppress PTH secretion by bovine parathyroid cells. Nephrol Dial Transplant. 2006 Mar;21(3):644-50.|[2]Noonan W, Koch K, Nakane M, Ma J, Dixon D, Bolin A, Reinhart G. Differential effects of vitamin D receptor activators on aortic calcification and pulse wave velocity in uraemic rats. Nephrol Dial Transplant. 2008 Dec;23(12):3824-30.|[3]Sj?dén G. Effects of vitamin D. A comparison of 1 alpha OHD2 and 1 alpha OHD3 in rats. Acta Orthop Scand Suppl. 1985;217:1-84.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported