(S,R,S)-AHPC-Boc

(S,R,S)-AHPC-Boc

• Product Name Alternative: VH032-Boc
• CAS Number: 1448189-98-7
• UNSPSC Description: (S,R,S)-AHPC-Boc (VH032-Boc) is a ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Boc is used in PROTAC technology[1].
• Target Antigen: Ligands for E3 Ligase
• Type: Reference compound
• Related Pathways: PROTAC
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/s-r-s-ahpc-boc.html
• Purity: 99.15
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(OC(C)(C)C)N[C@@H](C(C)(C)C)C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O
• Molecular Weight: 530.68
• References & Citations: [1]Zengerle M, et al. Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4. ACS Chem Biol. 2015;10(8):1770‐1777.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, stored under nitrogen)
• Clinical Information: No Development Reported