Products for Research Use Only
RegisterLogin

Human CellExp™ CD33/SIGLEC-3

CAT: 0026-P1616-20Size: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0026-P1616-20Size:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CD33 is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This single-pass type I membrane protein contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like Vtype (immunoglobulin-like) domain. It is considered myeloid-specific, but it can also be found on some lymphoid cells. It binds to α2-6- and α2-3-sialylated glycans and sialylated ligands. It acts as an inhibitory receptor since, when it is crosslinked, it becomes phosphorylated on its cytoplasmic ITIM sequence that recruits SHP-1 and SHP-2 phosphatases and negatively regulates cell activation in both myeloid cell lines and activated NK cells. It induces apoptosis in acute myeloid leukemia and is a target for the treatment of leukemia.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
12 months

Related Products

CatalogName
P1343-50Human CellExp™ Siglec-15, Human Recombinant
P1343-10Human CellExp™ Siglec-15, Human Recombinant
P1466-50Human CellExp™ Siglec-15, Mouse Recombinant
P1466-10Human CellExp™ Siglec-15, Mouse Recombinant
P1480-50Human CellExp™ MAG / Siglec-4a, Human Recombinant
P1480-10Human CellExp™ MAG / Siglec-4a, Human Recombinant
P1330-50Human CellExp™ Siglec-2 / CD22, Mouse Recombinant
P1330-10Human CellExp™ Siglec-2 / CD22, Mouse Recombinant
P1487-10Human CellExp™ Siglec-2, Fc Tag, Human Recombinant
P1487-50Human CellExp™ Siglec-2, Fc Tag, Human Recombinant

Alternative Products

CatalogName
HY-P73643Siglec-3/CD33, Human (HEK293)
MBS554202-01Human CD33 (Siglec-3) Recombinant
IT-300-076p-01Human CD33 / Siglec-3 Protein
TMPY-04805-01Siglec-3/CD33 Protein, Human, Recombinant
HY-P73642-01Siglec-3/CD33, Human (HEK293, hFc)
RP00554-01Recombinant Human Siglec-3/CD33 Protein
HA210949-01Human Siglec-3/CD33, Tag Free
E24PHA059Human Siglec-3 / CD33, His Tag
HY-P73644Siglec-3/CD33, Human (HEK293, His)
MBS9141711-01Recombinant Human CD33/Siglec-3 Protein

Popular Products