Eftilagimod alfa

• CAS Number :

  [1800476-36-1]

• UNSPSC Description :

  Eftilagimod alfa (IMP321) is a recombinant LAG-3Ig fusion protein that binds to MHC class II. Eftilagimod alfa mediates antigen-presenting cell (APC) activation followed by CD8 T-cell activation. Eftilagimod alfa can be used for metastatic melanoma and metastatic breast carcinoma research[1].

• Target Antigen :

  LAG-3

• Type :

  Inhibitory Antibodies

• Related Pathways :

  Immunology/Inflammation

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/eftilagimod-alfa.html

• Purity :

  95.98

• Solubility :

  H2O

• Smiles :

  [Eftilagimodalfa]

• References & Citations :

  [1]Atkinson V, et al. Eftilagimod alpha, a soluble lymphocyte activation gene-3 (LAG-3) protein plus pembrolizumab in patients with metastatic melanoma. J Immunother Cancer. 2020 Nov;8(2):e001681.

• Shipping Conditions :

  Dry Ice

• Storage Conditions :

  Store at -80°C for 2 years

• Clinical Information :

  Phase 2