Eftilagimod alfa

CAT: 0804-HY-P99933Size: 1 mgDry Ice: YesHazardous: No
CAT#:0804-HY-P99933Size:1 mg
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AVAILABILITY: InStock
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CAS Number
[1800476-36-1]
UNSPSC Description
Eftilagimod alfa (IMP321) is a recombinant LAG-3Ig fusion protein that binds to MHC class II. Eftilagimod alfa mediates antigen-presenting cell (APC) activation followed by CD8 T-cell activation. Eftilagimod alfa can be used for metastatic melanoma and metastatic breast carcinoma research[1].
Target Antigen
LAG-3
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eftilagimod-alfa.html
Purity
95.98
Solubility
H2O
Smiles
[Eftilagimodalfa]
References & Citations
[1]Atkinson V, et al. Eftilagimod alpha, a soluble lymphocyte activation gene-3 (LAG-3) protein plus pembrolizumab in patients with metastatic melanoma. J Immunother Cancer. 2020 Nov;8(2):e001681.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Clinical Information
Phase 2

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