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(-) -Taxifolin

CAT: 0804-HY-N0136B-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0136B-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(-) -Taxifolin is the less active enantiomer of Taxifolin. Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM[1]. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity[2].
CAS Number
111003-33-9
Product Name Alternative
(-) -Dihydroquercetin
UNSPSC
12352005
Target
Tyrosinase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/minus-taxifolin.html
Purity
98.98
Solubility
10 mM in DMSO
Smiles
O=C1[C@@H](O)[C@H](C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C13
Molecular Formula
C15H12O7
Molecular Weight
304.25
References & Citations
[1]Angelis A, et al. Bio-Guided Isolation of Methanol-Soluble Metabolites of Common Spruce (Picea abies) Bark by-Products and Investigation of Their Dermo-Cosmetic Properties. Molecules. 2016 Nov 21;21 (11) :1586.|[2]Lei Ren, et al. Dissecting Efficacy and Metabolic Characteristic Mechanism of Taxifolin on Renal Fibrosis by Multivariate Approach and Ultra-Performance Liquid Chromatography Coupled With Mass Spectrometry-Based Metabolomics Strategy. Front Pharmacol. 2021 Jan 14;11:608511.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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