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Casanthranol

CAT: 0804-HY-B2134-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B2134-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Casanthranol is a concentrated mixture of anthranol glycosides from cascara sagrada (dried bark of Rhamnus p.) . Casanthranol can be used as a laxative in constipation and various medical conditions, stimulant laxative. Casanthranol encourages bowel movements by acting on the intestinal wall to increase muscle contractions. Casanthranol is protective in a PFF-induced toxicity model (EC50 = 34.2 μM) of N2a cells[1][2].
CAS Number
8024-48-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Casanthranol.html
Solubility
DMSO : ≥ 50 mg/mL
Smiles
[Casanthranol]
Precautions
H302, H315, H319, H335
References & Citations
[1]NCIt. Casanthranol.|[2]Braun, A. R., et al., (2023) . Advancements in a FRET Biosensor for Live-Cell Fluorescence-Lifetime High-Throughput Screening of Alpha-Synuclein. ASN neuro, 15, 17590914231184086.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched

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BUP20873-01Casanthranol
TRC-C226503-1GCasanthranol (A mixture of Casanthranol A, Casanthranol B, Cascaroside A and Cascaroside B) (Technical Grade)

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