FA-PEG5-Mal

• Description :

  FA-PEG5-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• Product Name Alternative :

  Folic acid-PEG5-Mal

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  PROTAC Linkers

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/fa-peg5-mal.html

• Purity :

  99.46

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C1C2=C(N=C(N1)N)N=CC(CNC3=CC=C(C=C3)C(N[C@@H](CCC(NCCOCCOCCOCCOCCOCCN4C(C=CC4=O)=O)=O)C(O)=O)=O)=N2

• Molecular Formula :

  C35H45N9O12

• Molecular Weight :

  783.78

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PEG Linkers