Products for Research Use Only
RegisterLogin

Chiisanoside

CAT: 0804-HY-121152Size: InquireDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-121152Size:Inquire
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
89354-01-8
UNSPSC Description
Chiisanoside exhibits neuroprotective, anticancer, antidepressant, anti-inflammatory, anti-obesity and anti-platelet activities. Chiisanoside inhibits tumor growth in H22 xenograft mouse model, through immunoregulation, induction of apoptosis and inhibition of angiogenesis. Chiisanoside attenuates Parkinson’s disease through regulation of Parkin/ZNF746/PGC-1α axis, and promotion of mitochondrial biogenesis[1][2].
Target Antigen
Apoptosis; Dopamine Receptor; GABA Receptor; α-synuclein
Type
Natural Products
Related Pathways
Apoptosis;GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/chiisanoside.html
Solubility
10 mM in DMSO
Smiles
OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)C)O)O)O)O[C@H]1OC[C@H]([C@H]([C@@H]([C@H]3O)O)O)O[C@H]3OC([C@]45[C@@]([C@@H](CC5)C(C)=C)([H])[C@]6([H])[C@@](CC4)([C@]7([C@]8([H])[C@@](OC(C[C@H]([C@]8([C@@H](CC7)C(C)=C)C)O)=O)([H])C6)C)C)=O
Molecular Weight
955.09
References & Citations
[1]Hsu YL, et al., Chiisanoside Mediates the Parkin/ZNF746/PGC-1α Axis by Downregulating MiR-181a to Improve Mitochondrial Biogenesis in 6-OHDA-Caused Neurotoxicity Models In Vitro and In Vivo: Suggestions for Prevention of Parkinson's Disease. Antioxidants (Basel). 2023 Sep 20;12(9):1782.|[2]Bian X, et al., Chiisanoside, a triterpenoid saponin, exhibits anti-tumor activity by promoting apoptosis and inhibiting angiogenesis[J]. RSC advances, 2017, 7(66): 41640-41650.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

Alternative Products

CatalogName
M31364-01Chiisanoside

Popular Products