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Isomannide

CAT: 0804-HY-W013827-01Size: 25 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W013827-01Size:25 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Isomannide (1,4:3,6-Dianhydromannitol) is a common intermediate compound and derivative of Isosorbide. Some derivatives of isomannide have potent inhibitory effects on KLK5 and KLK7. Isomannide can be used in the research of HCV infection and KLK5/KLK7-related diseases[1][2][3].
CAS Number
641-74-7
Product Name Alternative
1,4:3,6-Dianhydromannitol
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents; Drug Derivative; Drug Intermediate
Type
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/isomannide.html
Purity
99.97
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O[C@H]1[C@]2([H])[C@@](OC1)([H])[C@@H](CO2)O
Molecular Formula
C6H10O4
Molecular Weight
146.14
Precautions
H302, H315, H319, H335
References & Citations
[1]Rose M, et al. Isosorbide as a renewable platform chemical for versatile applications--quo vadis? ChemSusChem. 2012 Jan 9;5 (1) :167-76.|[2]Barros TG, et al. Pseudo-peptides derived from isomannide: inhibitors of serine proteases. Amino Acids. 2010 Mar;38 (3) :701-9.|[3]Oliveira JP, et al. Isomannide-based peptidomimetics as inhibitors for human tissue kallikreins 5 and 7. ACS Med Chem Lett. 2013 Dec 6;5 (2) :128-32.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

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