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FPPS-IN-2

CAT: 0804-HY-163832Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163832Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FPPS-IN-2 (compound 4a) is a potent and orally active HFPPS inhibitor with an IC50 value of 1.108 µM. FPPS-IN-2 has the potential for the research of osteoporosis[1].
UNSPSC
12352005
Target
Farnesyl Transferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/fpps-in-2.html
Smiles
COC1=CC(/C=C/C(C)=O)=CC=C1OCCOC2=CC=C(/C=C/C(C)=O)C=C2OC
Molecular Formula
C24H26O6
Molecular Weight
410.46
References & Citations
[1]El-Sayed NF, et al. Farnesyl pyrophosphate synthase inhibitors with antiosteoporosis efficacy in ovariectomized rats: A mixed binding approach beyond bisphosphonates. Eur J Med Chem. 2024 Jul 14;276:116679.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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