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L-Arginine

CAT: 0804-HY-N0455-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0455-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-Arginine ((S) - (+) -Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis[1][2][3][4][5].
CAS Number
74-79-3
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; NO Synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-arginine.html
Purity
99.89
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
N[C@@H](CCCNC(N)=N)C(O)=O
Molecular Formula
C6H14N4O2
Molecular Weight
174.20
Precautions
H302, H315, H319, H335
References & Citations
[1]Tapiero H, et al. I. Arginine. Biomed Pharmacother. 2002 Nov;56 (9) :439-45.|[2]Bakker J, et al. Administration of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) by intravenous infusion for up to 72 hours can promote the resolution of shock in patients with severe sepsis: results of a randomized, double-blind, placebo-controlled multicenter study (study no. 144-002) . Crit Care Med. 2004 Jan;32 (1) :1-12.|[3]Yamada M, et al. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab. 2000 Apr;20 (4) :709-17.|[4]Mizunuma T, et al. Effects of injecting excess arginine on rat pancreas. J Nutr. 1984 Mar;114 (3) :467-71.|[5]Siriviriyakul P, et al. Effects of curcumin on oxidative stress, inflammation and apoptosis in L-arginine induced acute pancreatitis in mice. Heliyon. 2019 Aug 27;5 (8) :e02222.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
ENOS; Human Endogenous Metabolite; Microbial Metabolite

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CatalogName
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A0013-01L (+) -Arginine

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