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NSC668036

CAT: 0804-HY-117666-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-117666-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NSC668036 is a Dishevelled (Dvl) PDZ domain inhibitor with a Kd of 237 μM. NSC668036 blocks Wnt signaling by interrupting the Frizzled-Dvl interaction[1].
CAS Number
144678-63-7
Product Name Alternative
21-desDFZ
UNSPSC
12352211
Target
Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nsc668036.html
Purity
99.9
Solubility
DMSO : 25 mg/mL (ultrasonic) |H2O : ≥ 5mg/mL
Smiles
C[C@@H](C(O[C@@H](C(C)C)C(N[C@@H](C)C(O[C@@H](C(C)C)C(O)=O)=O)=O)=O)NC(OC(C)(C)C)=O
Molecular Formula
C21H36N2O9
Molecular Weight
460.52
References & Citations
[1]Jufang Shan, et al. Identification of a specific inhibitor of the dishevelled PDZ domain. Biochemistry. 2005 Nov 29;44 (47) :15495-503.|[2]Cong Wang, et al. Targeted inhibition of disheveled PDZ domain via NSC668036 depresses fibrotic process. Exp Cell Res. 2015 Feb 1;331 (1) :115-122.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
BA9100-1NSC668036

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