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NHPI-PEG4-C2-NHS ester

CAT: 0804-HY-130091-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-130091-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NHPI-PEG4-C2-NHS ester is an ADC Linker, which can be used to synthesize antibody-drug conjugates (ADCs) [1].
CAS Number
1415328-95-8
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nhpi-peg4-c2-nhs-ester.html
Purity
98.89
Solubility
10 mM in DMSO
Smiles
O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCON(C(C2=C3C=CC=C2)=O)C3=O
Molecular Formula
C23H28N2O11
Molecular Weight
508.48
Precautions
H302, H315, H319, H335
References & Citations
[1]Shailaja SRINAGESH, et al. Novel polypeptide small molecule conjugates and their uses
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported

Chemical Information

NHPI-PEG4-C2-NHS ester
CAS Number1415328-95-8
PubChem CID89284647
IUPAC Name(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(1,3-dioxoisoindol-2-yl)oxyethoxy]ethoxy]ethoxy]ethoxy]propanoate
Molecular FormulaC23H28N2O11
Molecular Weight508.5
XLogP-0.7
Topological Polar Surface Area147
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count11
Rotatable Bond Count18
Heavy Atom Count36
Formal Charge0
Complexity750
SMILES
C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCON2C(=O)C3=CC=CC=C3C2=O
InChI
InChI=1S/C23H28N2O11/c26-19-5-6-20(27)24(19)36-21(28)7-8-31-9-10-32-11-12-33-13-14-34-15-16-35-25-22(29)17-3-1-2-4-18(17)23(25)30/h1-4H,5-16H2
InChIKey
HLAGLPXQSIDIDX-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of NHPI-PEG4-C2-NHS ester
CAS: 1415328-95-8
CID: 89284647
Formula: C23H28N2O11
MW: 508.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight508.5
XLogP3-0.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count11
Rotatable Bond Count18
Exact Mass508.16930971
Monoisotopic Mass508.16930971
Topological Polar Surface Area147 Ų
Heavy Atom Count36
Formal Charge0
Complexity750
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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