Latrepirdine

CAT: 0804-HY-14862-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-14862-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Latrepirdine is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors. Latrepirdine stimulates amyloid precursor protein (APP) catabolism and amyloid-β (Aβ) secretion.

CAS Number

3613-73-8

Product Name Alternative

Dimebolin; Dimebone

UNSPSC

12352005

Hazard Statement

H302-H315-H320-H335

Target

5-HT Receptor; Adrenergic Receptor; Amyloid-β; Autophagy; Histamine Receptor

Type

Reference compound

Related Pathways

Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/Latrepirdine.html

Purity

99.19

Solubility

DMSO : 50 mg/mL (ultrasonic; warming)

Smiles

CC1=CC=C(CCN2C3=C(CN(C)CC3)C4=C2C=CC(C)=C4)C=N1

Molecular Formula

C21H25N3

Molecular Weight

319.44

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Steele JW, et al. Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model. Mol Psychiatry. 2013 Aug;18 (8) :889-97.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Alternative Products

Catalog	Name
B1572-10	Latrepirdine
164738	Latrepirdine Dihydrochloride
S1245-01	Latrepirdine 2HCl
300220	Latrepirdine HCl
AR-L06670-01	Latrepirdine DiHCl
AR-L06669-01	Latrepirdine Impurity 1
AR-L06668-01	Latrepirdine N-Oxide
AR-L06671-01	Latrepirdine Impurity 2

Latrepirdine

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