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Faropenem sodium

CAT: 0804-HY-76260-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-76260-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Faropenem sodium is an orally bioavailable penem antibiotic. Faropenem sodium regulates inorganic phosphate transporter Npt1. Faropenem sodium inhibits M. tuberculosis (MIC of 1.3 μg/mL) and B. anthracis[1][2].
CAS Number
122547-49-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Faropenem_sodium.html
Purity
98.87
Solubility
DMSO : 25 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C([C@@]([H])1[C@@H](C)O)N([C@@H]1S2)C(C(O[Na])=O)=C2[C@@H]3OCCC3
Molecular Formula
C12H14NNaO5S
Molecular Weight
307.30
Precautions
H302, H315, H319, H335
References & Citations
[1]Dhar N, et al. Rapid cytolysis of Mycobacterium tuberculosis by faropenem, an orally bioavailable β-lactam antibiotic. Antimicrob Agents Chemother. 2015 Feb;59 (2) :1308-19.|[2]Uchino H, et al. Faropenem transport across the renal epithelial luminal membrane via inorganic phosphate transporter Npt1. Antimicrob Agents Chemother. 2000 Mar;44 (3) :574-7.|[3]Gill SC, et al. Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. Antimicrob Agents Chemother. 2010 May;54 (5) :1678-83.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
J Glob Antimicrob Resist. 2025 Aug 8:44:435-441.|Int J Antimicrob Agents. 2022 Nov-Dec;60 (5-6) :106669.

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