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CZC-25146

CAT: 0026-B2941-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2941-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CZC-25146 is a potent inhibitor of Leucine-rich repeat kinase 2 (LRRK2) with an IC₅₀ of 4.76 nM. Mutations in LRRK2 are associated with Parkinson's disease. CZC-25146 attenuates LRRK2 G2019S mutant induced neuronal injury with EC₅₀ values of ~100 nM and 4 nM in primary rodent and human neurons respectively.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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