L321-NH-C3-PEG3-C1-NH2

L321-NH-C3-PEG3-C1-NH2

• UNSPSC Description: L321-NH-C3-PEG3-C1-NH2 (CRBN ligand L321 (HY-169359)) is an E3 Ligase Ligand-Linker Conjugate for BRD4 PROTAC L134 (HY-169358)[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/l321-nh-c3-peg3-c1-nh2.html
• Smiles: CC1=CC=C(C(/C=C2C(NC3=C\2C=CC(C(F)(F)F)=C3)=O)=C1)OCC(NCCCOCCOCCOCCCN)=O
• Molecular Weight: 579.61
• References & Citations: [1]Man Zhao, et al. Design, Synthesis, and Activity Evaluation of BRD4 PROTAC Based on Alkenyl Oxindole-DCAF11 Pair. J Med Chem. 2024 Nov 14;67(21):19428-19447.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported