Rilopirox

CAT: 0804-HY-113863-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-113863-01Size:1 mg

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Description

Rilopirox (HOE 351) is a hydroxy-pyridone compound with antimycotic properties. Rilopirox, a chelating agent, can inhibit catalase. Rilopirox inhibits the respiratory chain. Rilopirox inhibits growth of yeast isolates with a MIC50 of 4 μg/mL. Rilopirox has the potential for vaginal candidosis and oropharyngeal Candida infections research[1][2].

CAS Number

104153-37-9

Product Name Alternative

HOE 351

UNSPSC

12352005

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/rilopirox.html

Smiles

O=C1C=C(C)C=C(COC2=CC=C(OC3=CC=C(Cl)C=C3)C=C2)N1O

Molecular Formula

C19H16ClNO4

Molecular Weight

357.79

References & Citations

[1]R Kruse, et al. Studies for the elucidation of the mode of action of the antimycotic hydroxypyridone compound, rilopirox. Pharmacology. 1991;43 (5) :247-55.|[2]P Nenoff, et al. In vitro activity of rilopirox against fluconazole-susceptible and fluconazole-resistant Candida isolates from patients with HIV infection. Mycoses. 1999 Apr;42 (1-2) :55-60.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

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