Products for Research Use Only
RegisterLogin

Carglumic Acid (Standard)

CAT: 0804-HY-B0711R-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0711R-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Carglumic Acid (Standard) is the analytical standard of Carglumic Acid. This product is intended for research and analytical applications. Carglumic acid (N-Carbamyl-L-glutamic acid), a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator, is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency.
CAS Number
1188-38-1
Product Name Alternative
N-Carbamyl-L-glutamic acid (Standard)
UNSPSC
12352211
Hazard Statement
H315-H319-H335
Target
Others; Reference Standards
Type
Reference Standards
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/carglumic-acid-standard.html
Purity
99.91
Smiles
O=C(O)CC[C@@H](C(O)=O)NC(N)=O
Molecular Formula
C6H10N2O5
Molecular Weight
190.15
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Chen CT, et al. Carglumic acid promotes apoptosis and suppresses cancer cell proliferation in vitro and in vivo. Am J Cancer Res. 2015 Nov 15;5 (12) :3560-9.|[2]Chen CT, et al. Carglumic acid promotes apoptosis and suppresses cancer cell proliferation in vitro and in vivo. Am J Cancer Res. 2015 Nov 15;5 (12) :3560-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
Launched

Chemical Information

Carglumic Acid

Carglumic acid is a urea that is the N-carbamoyl derivative of L-glutamic acid. An orphan drug used to treat a deficiency in the enzyme N-acetylglutamate synthase, which leads to acute hyperammonaemia. It has a role as an orphan drug and a carbamylphosphate synthetase I activator. It is a N-acyl-L-glutamic acid and a member of ureas. It is a conjugate acid of a N-carbamoyl-L-glutamate(2-).

CAS Number1188-38-1
PubChem CID121396
IUPAC Name(2S)-2-(carbamoylamino)pentanedioic acid
Molecular FormulaC6H10N2O5
Molecular Weight190.15
XLogP-2.4
Topological Polar Surface Area130
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Heavy Atom Count13
Formal Charge0
Complexity227
SMILES
C(CC(=O)O)[C@@H](C(=O)O)NC(=O)N
InChI
InChI=1S/C6H10N2O5/c7-6(13)8-3(5(11)12)1-2-4(9)10/h3H,1-2H2,(H,9,10)(H,11,12)(H3,7,8,13)/t3-/m0/s1
InChIKey
LCQLHJZYVOQKHU-VKHMYHEASA-N
Chemical Structure
2D Structure
2D structure of Carglumic Acid
CAS: 1188-38-1
CID: 121396
Formula: C6H10N2O5
MW: 190.15
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight190.15
XLogP3-2.4
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass190.05897142
Monoisotopic Mass190.05897142
Topological Polar Surface Area130 Ų
Heavy Atom Count13
Formal Charge0
Complexity227
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-B0711-01Carglumic Acid
HY-N9457RNorcholic acid (Standard)
HY-N2998RGanoderenic acid A (Standard)
HY-N2318RPodocarpic acid (Standard)
HY-W338852R-01Gentisuric acid (Standard)
HY-W127758RAlginic acid (Standard)
HY-W115529RGeranic acid (Standard)
HY-W037875Rα-Acetamidocinnamic acid (Standard)
HY-W015881R-01Dimebutic acid (Standard)
HY-W012241R-01Dodecanedioic acid (Standard)

Alternative Products

CatalogName
T0755-01Carglumic Acid
RM-C071201-01Carglumic Acid Impurity (1-Carglumic Dimer)
A17588-1000Carglumic Acid 1g
A17588-500Carglumic Acid 500mg
A17588-250Carglumic Acid 250mg
AR-C06276-01D-Carglumic Acid
AR-C01441-01Carglumic Acid-d5
A17588-200Carglumic Acid 200mg
RM-C071205-01Carglumic Acid Impurity 5
AR-C01442-01Carglumic Acid Impurity C

Popular Products