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Tinurilimab

CAT: 0804-HY-P99051-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99051-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tinurilimab (Bay 1834942) is an anti-CEACAM6 (carcinoembryonic antigen-related cell adhesion molecule 6) humanized IgG2 monoclonal antibody. CEACAM6 is an immune checkpoint regulator suppressing the activity of effector T-cells against tumors. Tinurilimab shows an increased tumor cell killing effect in the tumor-cell/T-cell co-culture system[1].
CAS Number
2226224-30-0
Product Name Alternative
BAY 1834942
UNSPSC
12352203
Target
Transmembrane Glycoprotein
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tinurilimab.html
Purity
98.01
Solubility
H2O
Smiles
[Tinurilimab]
Molecular Weight
(144.76 kDa)
References & Citations
[1]Pinkert J, et al. T cell-mediated elimination of cancer cells by blocking CEACAM6-CEACAM1 interaction. Oncoimmunology. 2021 Dec 30;11 (1) :2008110.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 1

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