Protein Kinase C (beta) Peptide

Protein Kinase C (beta) Peptide

• CAS Number: 309247-50-5
• UNSPSC Description: Protein Kinase C (beta) Peptide is a peptide fragment of Protein Kinase Cβ. Protein Kinase Cβ is related with hyperglycemia decreases endothelium-derived nitric oxide. Inhibition of Protein kinase Cβ prevents the reduction in endothelium-dependent vasodilation induced by acute hyperglycemia[1].
• Target Antigen: PKC
• Type: Peptides
• Related Pathways: Epigenetics;TGF-beta/Smad
• Applications: Cancer-Kinase/protease
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/protein-kinase-c-beta-peptide.html
• Solubility: 10 mM in DMSO
• Smiles: O=C([C@H]1N(CCC1)C(CN)=O)N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N2[C@@H](CCC2)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CC(O)=O)C(N[C@@H](CS)C(O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
• Molecular Weight: 1966.18
• References & Citations: [1]Beckman JA, et al. Inhibition of protein kinase Cbeta prevents impaired endothelium-dependent vasodilation caused by hyperglycemia in humans. Circ Res. 2002;90(1):107-111.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported