(4E) -SUN9221

• Description :

  (4E) -SUN9221 is a potent antagonist of α1-adrenergic receptor and 5-HT2 receptor, with antihypertensive and anti-platelet aggregation activities.

• UNSPSC :

  12352005

• Target :

  5-HT Receptor; Adrenergic Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Cardiovascular Disease; Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/Pyrrolo[2,3-c]azepine-4,8_1H,5H_-dione,_1-[4-[4-_4-fluorobenzoyl_-1-piperidinyl]butyl]-6,7-dihydro-7-methyl-,_4-oxime,__4E_-.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=C/2C=CN1CCCCN3CCC(C(C4=CC=C(F)C=C4)=O)CC3)N(C)CCC2=N/O

• Molecular Formula :

  C25H31FN4O3

• Molecular Weight :

  454.54

• References & Citations :

  [1]Mizuno A, et al. Synthesis and pharmacological evaluation of pyrroloazepine derivatives as potent antihypertensive agents with antiplatelet aggregation activity. Chem Pharm Bull (Tokyo) . 1999 Feb;47 (2) :246-56.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  α-1 microglobulin

• CAS Number :

  [222318-55-0]