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FRG8701

CAT: 0804-HY-U00238Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-U00238Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FRG-8701 is a new Histamine H2-receptor antagonist with an IC50 of ranging from 0.25 to 0.43 μM.
CAS Number
108498-50-6
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/FRG8701.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCCOC1=CC=CC(CN2CCCCC2)=C1)CS(CC3=CC=CO3)=O
Molecular Formula
C22H30N2O4S
Molecular Weight
418.55
References & Citations
[1]Shibata M, et al. Effects of FRG-8701 on gastric acid secretion, gastric mucosal lesions by necrotizing agents and experimental gastric or duodenal ulcer in rats. Jpn J Pharmacol. 1990 Nov;54 (3) :277-85.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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