PAF-AN-1

• UNSPSC Description:

  PAF-AN-1 is a platelet activating factor receptor (PAF) antagonist.

• Target Antigen:

  Platelet-activating Factor Receptor (PAFR)

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/2,3-Dihydro-5-[4-[2-_3,4,5-trimethoxyphenyl_ethyl]phenyl]imidazo[2,1-a]isoquinoline.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=C(OC)C(OC)=CC(CCC2=CC=C(C3=CC4=C(C5=NCCN53)C=CC=C4)C=C2)=C1

• Molecular Weight:

  440.53

• References & Citations:

  [1]EP0469477A1|[2]Houlihan WJ, et al. Structural modification of 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinoline platelet activating factor receptor antagonists. J Med Chem. 1993 Oct 15;36(21):3098-102.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  115621-84-6