PAF-AN-1

• Description :

  PAF-AN-1 is a platelet activating factor receptor (PAF) antagonist.

• UNSPSC :

  12352005

• Target :

  Platelet-activating Factor Receptor (PAFR)

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology; Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/2,3-Dihydro-5-[4-[2-_3,4,5-trimethoxyphenyl_ethyl]phenyl]imidazo[2,1-a]isoquinoline.html

• Solubility :

  10 mM in DMSO

• Smiles :

  COC1=C(OC)C(OC)=CC(CCC2=CC=C(C3=CC4=C(C5=NCCN53)C=CC=C4)C=C2)=C1

• Molecular Formula :

  C28H28N2O3

• Molecular Weight :

  440.53

• References & Citations :

  [1]EP0469477A1|[2]Houlihan WJ, et al. Structural modification of 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinoline platelet activating factor receptor antagonists. J Med Chem. 1993 Oct 15;36 (21) :3098-102.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [115621-84-6]