Pancreatic Polypeptide, bovine

Pancreatic Polypeptide, bovine

• CAS Number: 179986-89-1
• UNSPSC Description: Pancreatic Polypeptide, bovine, a 36-amino acid, straight chain polypeptide derived primarily from the pancreas, inhibits secretin- and cholecystokinin-stimulated pancreatic secretion; Pancreatic Polypeptide, bovine acts as an agonist of NPY receptor, with high affinity at NPYR4.
• Target Antigen: Neuropeptide Y Receptor
• Type: Peptides
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease; Endocrinology
• Assay Protocol: https://www.medchemexpress.com/Pancreatic_Polypeptide,_bovine.html
• Solubility: 10 mM in H2O
• Smiles: O=C(N1[C@@H](CCC1)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N2[C@@H](CCC2)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC3=CC=C(C=C3)O)C(N4[C@@H](CCC4)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](C)C(N[C@@H]([C@H](O)C)C(N5[C@@H](CCC5)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCSC)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC6=CC=C(C=C6)O)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC7=CC=C(C=C7)O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(N[C@@H](CCSC)C(N[C@@H](CC(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCNC(N)=N)C(N8[C@@H](CCC8)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC9=CC=C(C=C9)O)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N
• Molecular Weight: 4225.78
• References & Citations: [1]Khan D, et al. Influence of neuropeptide Y and pancreatic polypeptide on islet function and beta-cell survival. Biochim Biophys Acta. 2017 Apr;1861(4):749-758.|[2]Louie DS, et al. Action of pancreatic polypeptide on rat pancreatic secretion: in vivo and in vitro. Am J Physiol. 1985 Oct;249(4 Pt 1):G489-95.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported