CMD178

• Description :

  CMD178 is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development[1].

• UNSPSC :

  12352209

• Target :

  STAT

• Type :

  Peptides

• Related Pathways :

  JAK/STAT Signaling; Stem Cell/Wnt

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/CMD178.html

• Solubility :

  10 mM in DMSO|10 mM in Ethanol|10 mM in H2O|H2O

• Smiles :

  F[R](F)[K].[Y]OCC1=CC=CC=C1

• Molecular Formula :

  C46H59N9O7

• Molecular Weight :

  850.03

• References & Citations :

  [1]Price-Troska T, et, al. Inhibiting IL-2 signaling and the regulatory T-cell pathway using computationally designed peptides. Invest New Drugs. 2019 Feb;37 (1) :9-16.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported