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CMD178

CAT: 0804-HY-P1453Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P1453Size:1 Each
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Description
CMD178 is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development[1].
UNSPSC
12352209
Target
STAT
Type
Peptides
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/CMD178.html
Solubility
10 mM in DMSO|10 mM in Ethanol|10 mM in H2O|H2O
Smiles
F[R](F)[K].[Y]OCC1=CC=CC=C1
Molecular Formula
C46H59N9O7
Molecular Weight
850.03
References & Citations
[1]Price-Troska T, et, al. Inhibiting IL-2 signaling and the regulatory T-cell pathway using computationally designed peptides. Invest New Drugs. 2019 Feb;37 (1) :9-16.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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