CMD178

• UNSPSC Description:

  CMD178 is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development[1].

• Target Antigen:

  STAT

• Type:

  Peptides

• Related Pathways:

  JAK/STAT Signaling;Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/CMD178.html

• Solubility:

  10 mM in DMSO|10 mM in Ethanol|10 mM in H2O|H2O

• Smiles:

  F[R](F)[K].[Y]OCC1=CC=CC=C1

• Molecular Weight:

  850.03

• References & Citations:

  [1]Price-Troska T, et, al. Inhibiting IL-2 signaling and the regulatory T-cell pathway using computationally designed peptides. Invest New Drugs. 2019 Feb;37(1):9-16.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported