Cyclosporin A-Derivative 1 (Free base)

Cyclosporin A-Derivative 1 (Free base)

• CAS Number: 286852-20-8
• UNSPSC Description: Cyclosporin A-Derivative 1 (Free base) is a crystalline intermediate derived from the opening of cyclosporin A extracted from patent WO 2013167703 A1. Cyclosporin A is an immunosuppressive agent which can bind to the cyclophilin and inhibit calcineurin.
• Target Antigen: Calcineurin; Cyclophilin
• Type: Peptides
• Related Pathways: Immunology/Inflammation;Neuronal Signaling
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/Cyclosporin_A-Derivative_1_Free_base.html
• Purity: 98.80
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C([C@@](C(C)C)([H])N(C)C([C@H](CC(C)C)N(C)C([C@H](CC(C)C)N(C)C([C@@H](C)NC([C@H](C)NC([C@H](CC(C)C)N(C)C([C@@](C(C)C)([H])NC([C@H](CC(C)C)NC)=O)=O)=O)=O)=O)=O)=O)N(C)[C@]([C@H](OC(C)=O)[C@H](C)C/C=C/C)([H])C(N[C@@H](CC)C(N(C)CC(OC)=O)=O)=O
• Molecular Weight: 1276.69
• References & Citations: [1]Fabrice Gallou, et al. Process for the manufacture of cyclic undecapeptides. WO 2013167703 A1.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported