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Carperitide

CAT: 0804-HY-P1235Size: 1 EachDry Ice: NoHazardous: No
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Description
Carperitide (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. Carperitide (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine) inhibits endothelin-1 secretion in a dose-dependent way.
CAS Number
89213-87-6
Product Name Alternative
Atrial Natriuretic Peptide (ANP) (1-28), human, porcine
UNSPSC
12352209
Hazard Statement
H302-H315-H319-H335
Target
Endothelin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cardiovascular Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Atrial_Natriuretic_Peptide__ANP___1-28_,_human,_porcine.html
Solubility
10 mM in H2O
Smiles
OC(C=C1)=CC=C1C[C@@H](C(O)=O)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@@H]2CSSC[C@@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N2)=O)=O)CC(C)C)=O)=O)CO)=O)CCC(N)=O)=O)C)=O)=O)([H])[C@@H](C)CC)=O)CCCNC(N)=N)=O)CC(O)=O)=O)CCSC)=O)CCCNC(N)=N)=O)=O)=O)CC3=CC=CC=C3)=O)NC([C@H](CO)NC([C@H](CO)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@@H](N)CO)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O
Molecular Formula
C127H203N45O39S3
Molecular Weight
3080.44
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Kohno M, et al. Atrial and brain natriuretic peptides inhibit the endothelin-1 secretory response to angiotensin II in porcine aorta. Circ Res. 1992 Feb;70 (2) :241-7.|[2]Kohno M, et al. Inhibition by atrial and brain natriuretic peptides of endothelin-1 secretion after stimulation with angiotensin II and thrombin of cultured human endothelial cells. J Clin Invest. 1991 Jun;87 (6) :1999-2004.|[3]Ballermann BJ, et al. Physiologic regulation of atrial natriuretic peptide receptors in rat renal glomeruli. J Clin Invest. 1985 Dec;76 (6) :2049-56.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
Launched
Citation 01
Biofabrication. 2023 Apr 12;15 (3) .|J Cell Mol Med. 2021 Oct;25 (20) :9660-9673.|Mol Biol Rep. 2024 Apr 15;51 (1) :506.

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