PGLa

• Description :

  PGLa, a 21-residue peptide, is an antimicrobial peptide. PGLa is a member of the magainin family of antibiotic peptides found in frog skin and its secretions[1].

• UNSPSC :

  12352209

• Target :

  Antibiotic; Bacterial

• Type :

  Peptides

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/PGLa.html

• Solubility :

  10 mM in H2O

• Smiles :

  NCC(N[C@@H](CCSC)C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](C)C(NCC(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(NCC(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@H](C(N)=O)CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C88H162N26O22S

• Molecular Weight :

  1968.45

• References & Citations :

  [1]Radchenko DS, et al. Does a methionine-to-norleucine substitution in PGLa influence peptide-membrane interactions? Biochim Biophys Acta. 2016 Sep;1858 (9) :2019-27.|[2]Bechinger B, et al. Structure and dynamics of the antibiotic peptide PGLa in membranes by solution and solid-state nuclear magnetic resonance spectroscopy. Biophys J. 1998 Feb;74 (2 Pt 1) :981-7.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [102068-15-5]