Phe-Met-Arg-Phe, amide

• UNSPSC Description:

  Phe-Met-Arg-Phe, amide dose dependently (ED50=23 nM) activates a K+ current in the peptidergic caudodorsal neurons.

• Target Antigen:

  Potassium Channel

• Type:

  Peptides

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/Phe-Met-Arg-Phe,_amide.html

• Solubility:

  10 mM in H2O

• Smiles:

  N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC2=CC=CC=C2)=O)=O)=O

• Molecular Weight:

  598.76

• References & Citations:

  [1]Kits KS, et al. Phe-Met-Arg-Phe-amide activates a novel voltage-dependent K+ current through a lipoxygenasepathway in molluscan neurones. J Gen Physiol. 1997 Nov;110(5):611-28.|[2]Sorenson RL, et al. Phe-met-arg-phe-amide (FMRF-NH2) inhibits insulin and somatostatin secretion and anti-FMRF-NH2 sera detects pancreatic polypeptide cells in the rat islet. Peptides. 1984 Jul-Aug;5(4):777-82.|[3]Ottlecz A, et al. Phe-Met-Arg-Phe-amide (FMRFamide) stimulated growth hormone secretion in conscious OVX rats. Neuropeptides. 1987 Feb-Mar;9(2):161-7.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  64190-70-1