Phellodendrine

• UNSPSC Description:

  Phellodendrine, a isoquinoline alkaloid, is one of important characteristic ingredients in the Phellodendron amurense. phellodendrine is against AAPH-induced oxidative stress through regulating the AKT/NF-κB pathway. Phellodendrine has good antioxidant, and anti-inflammatory effect [1].

• Target Antigen:

  Akt; NF-κB

• Type:

  Natural Products

• Related Pathways:

  NF-κB;PI3K/Akt/mTOR

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/phellodendrine.html

• Purity:

  99.60

• Solubility:

  DMSO : 5 mg/mL (ultrasonic)

• Smiles:

  OC1=C(OC)C=C2CC[N@@+]3(C)CC4=CC(OC)=C(O)C=C4C[C@@]3([H])C2=C1

• Molecular Weight:

  342.41

• References & Citations:

  [1]Li L , et al. The defensive effect of phellodendrine against AAPH-induced oxidative stress through regulating the AKT/NF-κB pathway in zebrafish embryos. Life Sci. 2016 Jul 15;157:97-106.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  6873-13-8