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(+) -Magnoflorine

CAT: 0804-HY-N0334Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N0334Size:1 Each
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Description
(+) -Magnoflorine (α-Magnoflorine) is an aporphine alkaloid and antifungal agent. (+) -Magnoflorine can be isolated from the aerial parts of Clematis parviloba. (+) -Magnoflorine shows potent antifungal activities against Penicillium avellaneum UC-4376 with a minimal inhibition amount of 5 μg/disc. (+) -Magnoflorine has significant antifungal activities against T. rubrum and T. mentagrophyte with MIC values of 62.5 μg/mL and 62.5 μg/mL, respectively[1][2].
CAS Number
2141-09-5
Product Name Alternative
Magnoflorine; α-Magnoflorine; Thalictrine
UNSPSC
12352005
Hazard Statement
H302+H312+H332
Target
Fungal
Type
Natural Products
Related Pathways
Anti-infection
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/magnoflorine.html
Solubility
10 mM in DMSO
Smiles
C[N+]1(C)CCC2=CC(OC)=C(O)C3=C2[C@]1([H])CC4=CC=C(OC)C(O)=C34
Molecular Formula
C20H24NO4+
Molecular Weight
342.41
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
References & Citations
[1]Chen JH, et al. Aporphine alkaloids from Clematis parviloba and their antifungal activity. Arch Pharm Res. 2009 Jan;32 (1) :3-5. |[2]Luo N, et al. Antifungal activity and potential mechanism of magnoflorine against Trichophyton rubrum. J Antibiot (Tokyo) . 2021 Mar;74 (3) :206-214.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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