Chavicol

• Description :

  Chavicol (p-Hydroxyallylbenzene, compound 6) can inhibit acetylcholinesterase (Cholinesterase (ChE) ), with an IC50 of 7.42 μM. Chavicol has anti-cancer activity and can suppress the growth, survival, migration, and invasion of cancer cells. Chavicol cytotoxic effect is significant, approximately 31 μg/mL in A-549 cells[1][2].

• Product Name Alternative :

  P-Hydroxyallylbenzene

• UNSPSC :

  12352005

• Hazard Statement :

  H316, H319, H335

• Target :

  Cholinesterase (ChE)

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/chavicol.html

• Purity :

  97.99

• Solubility :

  DMSO : 200 mg/mL (ultrasonic)

• Smiles :

  C=CCC1=CC=C(C=C1)O

• Molecular Formula :

  C9H10O

• Molecular Weight :

  134.18

• Precautions :

  H316, H319, H335

• References & Citations :

  [1]Haixiao Lu, et al. Tzumin A and B, two new lignan derivatives from the barks of Sassafras tzumu. Nat Prod Res. 2017 Apr;31 (7) :829-834.|[2]Chellasamy Panneerselvam, et al. Anticancer activity of bioactive compound chavicol as potential toxic against human lung cancer A549 cells. Journal of Drug Delivery Science and Technology. Volume 73, July 2022, 103442.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [501-92-8]