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FBN1 Antibody

CAT: 0013-GTR18126524Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18126524Size:0.1 mg
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Description
FBN1 Antibody
Product Name Alternative
FBN1, fibrillin 1, FBN, MASS, MFS1, OCTD, SGS, WMS, fibrillin 15
UniProt
P35555
Reactivity
Human
Immunogen
The immunogen for this antibody is: C-DASNIEDQSETEAN
Target
FBN1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
500 ug/mL
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Peptide ELISA: antibody detection limit dilution 1:4000.Western Blot:Preliminary experiments in Human Brain (Cerebellum), Heart, Kidney, Skeletal Muscle and Skin lysates gave no specific signal but low background (at antibody concentration up to 1μg/mL) .Immunofluorescence: Strong expression of the protein seen in the cytoplasm of U251 and Jurkat cells. Recommended concentration: 10μg/mL. Flow Cytometry: Flow cytometric analysis of Jurkat cells. Recommended concentration: 10μg/mL.
Prediction Reactivity
Bovine, Canine, Mouse, Rat
Tested Applications
ELISA, FC, IF
NCBI Accession Number
NP_000129.3
Host or Source
Goat
Preservative
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

UniProtKB · P35555

Fibrillin-1

FBN1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35555
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FBN1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2RUU0, D2JYH6, Q15972, Q75N87
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Disease

Aortic aneurysmDisease variantDwarfism

Ligand

Calcium

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

EGF-like domainRepeatSignal

Cellular component

Extracellular matrixSecreted

Molecular function

Heparin-bindingHormone

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