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Minaprine

CAT: 0804-HY-B0884Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-B0884Size:1 Each
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Description
Minaprine is a reversible inhibitor of MAO-A; weakly inhibit acetylcholinesterase; an antidepressant for treatment of depression.
CAS Number
25905-77-5
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Minaprine.html
Solubility
DMSO : ≥ 35 mg/mL
Smiles
CC1=CC(C2=CC=CC=C2)=NN=C1NCCN3CCOCC3
Molecular Formula
C17H22N4O
Molecular Weight
298.38
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Kan JP, et al. Effect of the antidepressant minaprine on both forms of monoamine oxidase in the rat. Biochem Pharmacol. 1986 Mar 15;35 (6) :973-8.|[2]Contreras JM, et al. Aminopyridazines as acetylcholinesterase inhibitors. J Med Chem. 1999 Feb 25;42 (4) :730-41.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

Chemical Information

Minaprine

Minaprine is a secondary amine, a member of pyridazines and a member of morpholines. It has a role as an antidepressant, a cholinergic drug, an antiparkinson drug, a serotonin uptake inhibitor and a dopamine uptake inhibitor.

CAS Number25905-77-5
PubChem CID4199
IUPAC Name4-methyl-N-(2-morpholin-4-ylethyl)-6-phenylpyridazin-3-amine
Molecular FormulaC17H22N4O
Molecular Weight298.4
XLogP2
Topological Polar Surface Area50.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Heavy Atom Count22
Formal Charge0
Complexity316
SMILES
CC1=CC(=NN=C1NCCN2CCOCC2)C3=CC=CC=C3
InChI
InChI=1S/C17H22N4O/c1-14-13-16(15-5-3-2-4-6-15)19-20-17(14)18-7-8-21-9-11-22-12-10-21/h2-6,13H,7-12H2,1H3,(H,18,20)
InChIKey
LDMWSLGGVTVJPG-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Minaprine
CAS: 25905-77-5
CID: 4199
Formula: C17H22N4O
MW: 298.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight298.4
XLogP32
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass298.17936134
Monoisotopic Mass298.17936134
Topological Polar Surface Area50.3 Ų
Heavy Atom Count22
Formal Charge0
Complexity316
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
M13782-01Minaprine
318276Minaprine dihydrochloride
BM166417Minaprine hydrochloride
A17722-100Minaprine dihydrochloride 100mg
A17722-50Minaprine dihydrochloride 50mg
A17722-500Minaprine dihydrochloride 500mg
A17722-25Minaprine dihydrochloride 25mg
MBS577054Minaprine 2 HCl
A17722-10mM-DMinaprine dihydrochloride 10mM * 1mL in DMSO

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