Carbenicillin

• Description :

  Carbenicillin is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin can interfere the cell wall synthesis while displaying low toxicity to plant tissue[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H312-H332

• Target :

  Antibiotic; Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/carbenicillin.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(C(C(O)=O)C3=CC=CC=C3)=O)N1C2=O)O

• Molecular Formula :

  C17H18N2O6S

• Molecular Weight :

  378.40

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

• References & Citations :

  [1]Scott RE, et, al. Synergistic activity of carbenicillin and gentamicin in experimental Pseudomonas bacteremia in neutropenic rats. Antimicrob Agents Chemother. 1976 Oct;10 (4) :646-51. |[2]Neu HC, et, al. Carbenicillin and ticarcillin. Med Clin North Am. 1982 Jan;66 (1) :61-77.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• Isoform :

  β-lactam

• Citation 01 :

  Antimicrob Agents Chemother. 2023 Jun 15;67 (6) :e0160322.|Microbiol Spectr. 2023 Feb 14;11 (1) :e0303822.|Microbiol Spectr. 2023 Jun 15;11 (3) :e0069223.|ChemRxiv. 2020 Apr.|J Antimicrob Chemother. 2025 Nov 5:dkaf408.|Molecules. 2025 Mar 9;30 (6) :1224.

• CAS Number :

  [4697-36-3]