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Bethanechol

CAT: 0804-HY-B0406Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-B0406Size:1 Each
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Description
Bethanechol (Carbamyl-β-methylcholine), a parasympathomimetic agent, is a mAChR agonist that exerts its effects via directly stimulating the mAChR (M1, M2, M3, M4, and M5) of the parasympathetic nervous system[1].
CAS Number
674-38-4
Product Name Alternative
Carbamyl-β-methylcholine
UNSPSC
12352211
Hazard Statement
H302-H312-H332
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Bethanechol.html
Solubility
10 mM in DMSO
Smiles
CC(OC(N)=O)C[N+](C)(C)C
Molecular Formula
C7H17N2O2
Molecular Weight
161.22
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
References & Citations
[1]Julia Yuen Hang Liu, et al. Acetylcholine exerts inhibitory and excitatory actions on mouse ileal pacemaker activity: role of muscarinic versus nicotinic receptors. Am J Physiol Gastrointest Liver Physiol. 2020 Jul 1;319 (1) :G97-G107.|[2]M J Fregly, et al. Bethanechol-induced water intake in rats: possible mechanisms of induction. Pharmacol Biochem Behav. 1982 Oct;17 (4) :727-32.|[3]Inderbir S. Padda, et al. Bethanechol. Treasure Island (FL) : StatPearls Publishing; 2020 Jan-.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
MAChR1; mAChR3; mAChR4; mAChR5
Citation 01
Research Square Preprint. 2022 Mar.|Cell Stem Cell. 2025 May 1;32 (5) :778-794.e10.