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Pentosan Polysulfate

CAT: 0804-HY-A0203Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-A0203Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pentosan Polysulfate is an orally bioavailable medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate also displays a potent and selective anti-HIV activity. Pentosan Polysulfatecan be used for the research of interstitial cystitis[1][2].
CAS Number
[37300-21-3]
UNSPSC
12352005
Hazard Statement
H301-H311-H331-H341
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Pentosan_Polysulfate.html
Solubility
DMSO : < 1 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
[PentosanPolysulfate]
Molecular Weight
4000-6000
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P403+P233-P405-P501
References & Citations
[1]Schuchman EH, et al. Pentosan polysulfate: a novel therapy for the mucopolysaccharidoses. PLoS One. 2013;8 (1) :e54459.|[2]Baba M, et al. Pentosan polysulfate, a sulfated oligosaccharide, is a potent and selective anti-HIV agent in vitro. Antiviral Res. 1988 Sep;9 (6) :335-43.|[3]Wu J, et al. Inhibition of inflammation by pentosan polysulfate impedes the development and progression of severe diabetic nephropathy in aging C57B6 mice. Lab Invest. 2011 Oct;91 (10) :1459-71.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
HIV-1

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