Micafungin

• UNSPSC Description:

  Micafungin (Mycamine; FK463) is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase.

• Target Antigen:

  Antibiotic; Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/micafungin.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@](NC(C(NC([C@@](C[C@@H](O)C1)([H])N1C2=O)=O)[C@H](O)[C@H](C3=CC(OS(=O)(O)=O)=C(O)C=C3)O)=O)([H])[C@H](O)CC(N)=O)N4[C@@](C(N[C@@H]([C@@H](C[C@@H](C(NC2[C@H](O)C)=O)NC(C5=CC=C(C6=NOC(C7=CC=C(OCCCCC)C=C7)=C6)C=C5)=O)O)O)=O)([H])[C@@H](O)[C@@H](C)C4

• Molecular Weight:

  1270.27

• References & Citations:

  [1]Micafungin, From WikipediaInfect Drug Resist. 2022: 7459-7473.|J Antimicrob Chemother. 2020 Aug 1;75(8):2133-2140.|J Microbiol Methods. 2021 Sep 10;106327.|Microorganisms. 2023 Jun 18, 11(6), 1608.|Microorganisms. 2023, 11(1), 23.|mSphere. 2018 Nov 14;3(6). pii: e00547-18.|mSphere. 2020 Oct 28;5(5):e00821-20.|Mycoses. 2021 Mar;64(3):282-291.|Antimicrob Agents Chemother. 2023 Jul 10;e0054323.|bioRxiv. 2024 May 14.|Chem Biol Interact. 2024 Jul 31:400:111179.|J Clin Microbiol. 2017 Jun;55(6):1883-1893.|PLoS Negl Trop Dis. 2019 Aug 20;13(8):e0007681. |Sci Rep. 2017 Feb 17;7:42886.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Launched

• CAS Number:

  235114-32-6