Heparin

• Description :

  Heparin is a highly sulfated glycosaminoglycan, that is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. Heparin significantly inhibits exosome-cell interactions.

• UNSPSC :

  12352211

• Hazard Statement :

  H302

• Target :

  Autophagy; Bacterial; Endogenous Metabolite; Thrombin

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Autophagy; Metabolic Enzyme/Protease

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Cardiovascular Disease; Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Heparin.html

• Solubility :

  H2O : 100 mg/mL

• Smiles :

  O[C@H]1[C@H](O[C@H]2[C@H](OS(O)(=O)=O)[C@@H](O)[C@H](OC)[C@H](C(O)=O)O2)[C@@H](COS(O)(=O)=O)O[C@H](OC)[C@@H]1NS(O)(=O)=O.[n]

• Precautions :

  H302

• References & Citations :

  [1]Capila I, et al. Heparin-protein interactions. Angew Chem Int Ed Engl. 2002 Feb 1;41 (3) :391-412.|[2]Ito M, et al. Inhibitory effect of dextran sulfate and heparin on the replication of human immunodeficiency virus (HIV) in vitro. Antiviral Res. 1987 Jul;7 (6) :361-7.|[3]Ganapathy R, et al. Effect of heparin and fractionated heparin on trophoblast invasion. Hum Reprod. 2007 Sep;22 (9) :2523-7.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Natural Products

• Clinical Information :

  Launched

• Isoform :

  Human Endogenous Metabolite

• CAS Number :

  [9005-49-6]