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Rosuvastatin-d6 (sodium)

CAT: 0804-HY-17504BS1Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-17504BS1Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rosuvastatin-d6 sodium is deuterium labeled Rosuvastatin sodium. Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
CAS Number
2070009-41-3
UNSPSC
12352005
Hazard Statement
H302
Target
Autophagy; HMG-CoA Reductase (HMGCR)
Type
Isotope-Labeled Compounds
Related Pathways
Autophagy; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Purity
98.60
Solubility
10 mM in DMSO
Smiles
O=C(O[Na])C[C@H](O)C[C@H](O)/C=C/C1=C(C(C([2H])([2H])[2H])C([2H])([2H])[2H])N=C(N(C)S(C)(=O)=O)N=C1C2=CC=C(C=C2)F
Molecular Formula
C22H21D6FN3NaO6S
Molecular Weight
509.56
Precautions
H302
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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T12759-01Rosuvastatin D6 Sodium
CS-O-06943Rosuvastatin-d6 Sodium
TRC-R700502-1MGRosuvastatin-d6 Sodium Salt
MBS6048486-01Rosuvastatin-d6, Sodium Salt
abx188869-01Rosuvastatin Sodium
RM-R192297-01Rosuvastatin-d6 Sodium Salt discontinued see RG-R192200
TRC-R225340-500MGRosuvastatin Sodium Salt
MBS5767519Rosuvastatin D3 sodium
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