Rapastinel

• UNSPSC Description:

  Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator with partial agonist properties.

• Target Antigen:

  iGluR

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/Rapastinel.html

• Purity:

  99.49

• Solubility:

  DMSO : ≥ 32 mg/mL

• Smiles:

  O=C(N(CCC1)[C@@H]1C(N[C@H](C(N)=O)[C@H](O)C)=O)[C@H](CCC2)N2C([C@@H](N)[C@H](O)C)=O

• Molecular Weight:

  413.47

• References & Citations:

  [1]Burgdorf J, et al. The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus. Neuroscience. 2015 Nov 12;308:202-11.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  Phase 3

• CAS Number:

  117928-94-6