Progesterone

Progesterone

• CAS Number: 57-83-0
• UNSPSC Description: Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
• Target Antigen: Endogenous Metabolite; Progesterone Receptor
• Type: Natural Products
• Related Pathways: Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
• Applications: COVID-19-immunoregulation
• Field of Research: Cardiovascular Disease; Cancer
• Assay Protocol: https://www.medchemexpress.com/Progesterone.html
• Purity: 99.79
• Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: CC([C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O
• Molecular Weight: 314.46
• References & Citations: [1]Schindler AE, et al. Classification and pharmacology of progestins. Maturitas. 2003 Dec 10;46 Suppl 1:S7-S16.|[2]Zava DT, et al. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med. 1998 Mar;217(3):369-78.|[3]Komesaroff PA, et al. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric. 2001 Jun;4(2):144-50.|[4]Girling JE, et al. Progesterone, but not estrogen, stimulates vessel maturation in the mouse endometrium. Endocrinology. 2007 Nov;148(11):5433-41. Epub 2007 Aug 9.|[5]Wong R, et al. Progesterone pharmacokinetics in the mouse: implications for potential stroke therapy. J Pharm Pharmacol. 2012 Nov;64(11):1614-20. |[6]Wang JY, et al. Licorice zinc suppresses melanogenesis via inhibiting the activation of P38MAPK and JNK signaling pathway in C57BL/6J mice skin. Acta Cir Bras. 2022 Dec 19;37(10):e371002.|[7]Hisayoshi NoRIMOTO, et al. Effects of keishibukuryoganryokayokuinin (gui-zhi-fu-ling-wanliao-jia-yiyiren) on the Epidermal Pigment Cells from DBA/2 Mice Exposed to Ultraviolet B (UVB) and/or Progesterone. The pharmaceutical Society of Japan. 2011, 131(11):1613-1619.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Launched