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Tasisulam

CAT: 0804-HY-14804-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14804-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tasisulam is a anticancer agent and induces apoptosis via the intrinsic pathway, resulting in cytochrome c release and caspase-dependent cell death. Tasisulam inhibits mitotic progression and induces vascular normalization[1].
CAS Number
519055-62-0
Product Name Alternative
LY 573636
UNSPSC
12352005
Hazard Statement
H315-H317-H319-H335
Target
Apoptosis; Molecular Glues
Type
Reference compound
Related Pathways
Apoptosis; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tasisulam.html
Purity
99.77
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(NS(=O)(C1=CC=C(Br)S1)=O)C2=CC=C(Cl)C=C2Cl
Molecular Formula
C11H6BrCl2NO3S2
Molecular Weight
415.11
Precautions
P261-P264-P271-P272-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
References & Citations
[1]Meier T, et al. Tasisulam sodium, an antitumor agent that inhibits mitotic progression and induces vascular normalization. Mol Cancer Ther. 2011 Nov;10 (11) :2168-78.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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