Deltasonamide 2

• Description:

  Deltasonamide 2 is a competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM[1].

• UNSPSC:

  12352005

• Target:

  Phosphodiesterase (PDE)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/deltasonamide-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=S (C1=CC=C (S (=O) (N (CC2=CC=C (Cl) C=C2) C3CCCC3) =O) C=C1) (N ([C@H]4CC[C@H] (N) CC4) CC5=NC (NC) =NC=C5) =O

• Molecular Formula:

  C30H39ClN6O4S2

• Molecular Weight:

  647.25

• References & Citations:

  [1]Klein CH, et al. PDEδ inhibition impedes the proliferation and survival of human colorectal cancer cell linesharboring oncogenic KRas. Int J Cancer. 2019 Feb 15;144 (4) :767-776.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2088485-34-9