Chrysene

• UNSPSC Description:

  Chrysene is a high molecular weight (HMW), polycyclic aromatic hydrocarbon (PAH) known for its recalcitrance and carcinogenic properties[1].

• Target Antigen:

  Biochemical Assay Reagents

• Type:

  Natural Products

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/chrysene.html

• Purity:

  99.81

• Solubility:

  DMSO : 2 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  C12=CC=CC=C1C=CC3=C4C=CC=CC4=CC=C23

• Molecular Weight:

  228.29

• References & Citations:

  [1]Vaidya S, et al. Degradation of Chrysene by Enriched Bacterial Consortium. Front Microbiol. 2018 Jun 26;9:1333.|[2]Wislocki PG, et al. Tumorigenicity of nitrated derivatives of pyrene, benz[a]anthracene, chrysene and benzo[a]pyrene in the newborn mouse assay. Carcinogenesis. 1986 Aug;7(8):1317-22.|[3]Jacob J, et al. Monooxygenase induction by various xenobiotics and its influence on rat liver microsomal metabolism of chrysene in comparison to benz[a]anthracene. Cancer Lett. 1987 Jan;34(1):91-102.|[4]Tao LP, et al. Chrysene, a four-ring polycyclic aromatic hydrocarbon, induces hepatotoxicity in mice by activation of the aryl hydrocarbon receptor (AhR). Chemosphere. 2021 Aug;276:130108.|[5]Hodgson RM, et al. Metabolic activation of chrysene in mouse skin: evidence for the involvement of a triol-epoxide. Carcinogenesis. 1983 Dec;4(12):1639-43.|[6]Rice JE, et al. Comparative tumor-initiating activity of methylene-bridged and bay-region methylated derivatives of benz[a]anthracene and chrysene. Carcinogenesis. 1988 Dec;9(12):2275-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  218-01-9